From more effective fish health diagnosis to the development of next-generation biofuels, marine biotechnology is driving remarkable discoveries. Researchers are discovering new compounds with therapeutic potential, designing resilient bio-hybrid systems that combine biology and computing, and exploring how marine resources can improve food production and environmental sustainability.
Advanced Techniques for Assessing Fish Health
This invention presents innovative methods for assessing the health status of fish populations and diagnosing diseases in affected individuals. More specifically, it focuses on the use of blood biomarkers as reliable indicators of health and disease in fish. Furthermore, the invention provides a method for determining a wellness score for fish populations, enabling a comprehensive assessment of their health.
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Innovative Feed for Fish Larvae: Production, Rearing, and Application Methods
A new feed for fish larvae has been developed with the aim of increasing growth and improving the respective survival rate of the larvae, as well as an optimized method for fish rearing. The feed (40) consists of a central part (10) formulated with fish-derived components, encapsulated by a gelatinous coating (20). The rearing method involves two sequential feeding phases: first, the larvae are fed live feed and, as soon as the initial feeding phase has begun, the feed formulated for larvae is administered to them (40).
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Genetic Engineering of the Marine Oleaginous Microalga Marinichlorella sp. NKG400014
Microalgae have long been considered a promising source of sustainable biofuels, but progress has been limited by a lack of effective genetic tools. In this study, an oil-rich marine microalga, Marinichlorella sp. NKG400014, was identified and its potential for biofuel production was evaluated. The first genetic transformation system for this strain was successfully developed using electroporation and testing different promoters and marker genes to optimize efficiency. Interestingly, the algae’s own promoters proved more effective than external ones. This discovery allows for the development of future genetic and metabolic engineering strategies that could significantly increase lipid production in this strain and contribute to the development of more sustainable biofuels.
PMC
Onnamides and a Novel Analog, Onnamide G, as Potent Agents against Leishmania
Leishmaniasis remains a major global health concern, with limited and ineffective treatment options. In this study, we identified onnamides from the marine sponge Theonella sp. as highly potent and selective agents against Leishmania major promastigotes (IC₅₀ = 0.2–140 nm), with low cytotoxicity towards human HepG2 cells. Structure-activity relationship analyses with 6,7-dihydro-onnamide A and its analogues, as well as comparisons with amphotericin B, highlight the unique mode of action of these compounds. Onnamides thus emerge as promising avenues for the development of new therapies against leishmaniasis.
PMC
Exploring how algae supplements influence the growth and health of broiler chickens.
This study explored the impact of adding seaweed—Sargassum, Gracilaria, and Spirulina—on broiler production. While growth performance remained unchanged, diets enriched with seaweed improved antioxidant status, increased HDL and serum protein levels, as well as omega-3 content, without affecting meat quality. These results show that seaweed can safely enrich poultry feed, promoting healthier and more nutritious products.
PMC
Bio-Hybrid Computing Systems Based on Proteinoids and Algae
Proteinoids, formed by heating amino acids, self-organize into microspheres that exhibit electrical activity similar to that of neurons. In this study, proteinoid microspheres were combined with the microalga *Emiliania huxleyi* to create bio-hybrid systems with neuromorphic properties. Microscopy revealed complex, self-organized structures, while electrical recordings showed distinct oscillatory patterns influenced by temperature and pH. These bioelectrical signals were used to perform basic Boolean logic operations, with the algae excelling in forward gates and the bio-hybrid mixture showing better performance in reverse gates. In summary, algae-proteinoid systems demonstrate promising potential for sustainable and biocompatible bio-hybrid computing.
PMC
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